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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18483daedceda3225a67b14e83bf70dfb687728d26303f33331ae5cd6d26fc18' 
  AND token = 'Xaq4TEd6sTqVCuYpbQWhP895F6LahVYsC9ZlIGv5jiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}