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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c5ef53a0230515fd6dd0b2e9e141e6b18bcd3b2e29b9c422a9fb6b05d1c12b' 
  AND token = '/dS1faQGijshdCs5/kLU7IwqcaKty09uccIejxf9IYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}