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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effbe98d10ca0f26c707d8f075523fc5fd641a0f76cbe88c765ab50cb96a05e7' 
  AND token = 'oBcjaWFI+BHestEZWQ18afEy3tQ0MavunaBrcdFcuGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}