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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cbaaddf250756026bf7914661f42a07fc31247864669b296e5d20e446729291' 
  AND token = 'Cr1FW8OxYmPd9ueE2lLhMs3Zb588R1dy6v4PI5rgko8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}