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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efdf76c0fc25a4b0495362a8e5401fffe0dd8a38d829100b6e69a319eed7244c' 
  AND token = 'k1l57Aq6t5F1eMrwVI7b3KCWKe1lsefUk05rsXsyfb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}