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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1051a08d1888c0b4abc9b614243e731863d90033bf29cba53a9c5222060ce716' 
  AND token = 'sfSCZaRSffXX0+Jkv3enoaapi5PC7aFaM6fsTe7oXi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}