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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87324df348c00c1512454e9aee6fd84970d0ac6cd785541f9cfcf5c5def892e2' 
  AND token = 'a8tRCa71b1lAd2meQBw71zn+PpJeiCz+u2puZ+DIj9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}