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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381f41e488366c2230cba8ff324d440a0c717f0e5d392cfaaf010f74581b3180' 
  AND token = 'b+WNfRDN/BcHLlhS863MyudCeO4YsV2SpmynjbTi5yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}