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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b75d885e774e2be77e2e504bb7875248797a666143de022928c672eacbfb1ed' 
  AND token = 'HGQxn9desNW0q0VY7xcU32EpFkS2/mSZodg53FpT3wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}