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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bde264a327ac81a865b2b86d2c289a43a3f29ceb3ee47a66c4cdb0c715717b97' 
  AND token = '4ABJR3XvHfdGG8Io7uNL62MRrvjUFWE3EkTDvPJPcr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}