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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc86cdbe27d454509c7da16309316fa2c31f97393f704310a255c5b08c94c0e' 
  AND token = 'VUdraLBtCukEqtDVYBf5C6DwVeTA4jKAvMXMVEoO8vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}