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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc73bbf1643d971ffefc4bf7c8fc06f886b73b2d157928cd93c72479c71afda7' 
  AND token = 'CZYyx35pOV1qTqzTSwUf9lVxGSxl5d7KA3gwg6Ouz7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}