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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7ff5fa11d692d8eb61b5d6f442f9deacec76c13a1e47ace43331f7b897a5e8a' 
  AND token = '+/fJY157Dx0xw7PqW1oFJM6j4OLaiY8FHAAmMlw2SJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}