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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be75e6c2503371644a0dadd73ef12be5cd867fff9738e06fdd8584ad8546cee' 
  AND token = 'ZKCo8xk/g8+Hz4HzTaxI+UMkrydbEvfRgi6PslXCXKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}