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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4153729e897c0116d3ab167cd68009c05b62e2641dd70ccab7215ca8675e1faa' 
  AND token = 'nTROTj4vhBbJOCAKDPDYa2OZu9MaxU692BZVQbd4j64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}