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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28aa774f4f445a4d1b1963c737db940c40b3e53be31f4e6b03b6bcd8532cc1a2' 
  AND token = 'c8yVSYR8kJQb1KQBFsW/buL+or3HBQyFFyJnzTE19x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}