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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '296e279d5c234118a8ffa220a413ab69c3c2a8b7b8cf832f079d54f7074ea6d4' 
  AND token = 'WTJHpUeULHGv6YDDTedPiAkaO3s6pX3e5+CQqcfCbbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}