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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f50fb036b88233b99184e6a0d47b64c44e365063f855316b4e0d7998f0a97e8' 
  AND token = 'jt/yCi2mfmL69RauhR6R/jaAXSYuCIoVLsqMb3R+g3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}