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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b442cacbb6c4608b6b23e6e53f51fa81900450315eb086051c0df51649ae5e8' 
  AND token = 'RWHuUHZ7bC93fbE55rRq/VmDGaoTpTy9q8Ugm5DR49M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}