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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e10a898571e3c6b5e27a29fcb4f2f42a078f9470ad09e7185eb30028bd891b' 
  AND token = 'VaVrGBOHfWCtkSp8TfIKyrc9rS9huYgV+SqkeUAwXJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}