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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '562a1fe7883c1ea2ee2b9d064e51f5a66ee354ca6f06094cedae7a602b4b2318' 
  AND token = 'shrMFcGl8/BLX5uOw8E9+clgpZssThveMMnqVXvmDEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}