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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f1107ae63921b8f9748b282b51744bbc2811cb6363403b2eed20e90897a400' 
  AND token = '8Ppxvk/s1/uNPF3rnT+s5t36fnYG45ERtnVPsJi/qNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}