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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68cffc6b5bcbfba9c31de163c2f6c6ccfd1cfcd91517af26936c3ebfe3b440ef' 
  AND token = 'lqHaA5keGt/zQ3y9SvdCkNiageiOb5qS3XQVFbsr7e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}