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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b84a531759379de84fd5e608c0ad5060fa06c6c2e27896dc5c43c1e06d8a194' 
  AND token = 'pQnK5KMxEEMS8e/mpEYd9mY8tu1wUbbmYZNQa56v2y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}