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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4f009bb3afb2087471f2981a6658c54347c0d2a558f01dc1fe9eb17154d6a9' 
  AND token = 'yqp8WraDHBeYI7lB9MWTqKy9Cu+I/jOz1ijGjd7nyf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}