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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d5f43ef7e0e694dfefd7a4df5326ae46f3045ca0f77e38ad98062dc0310915' 
  AND token = '+K09hpDuoMViEL7IUDY6QxGp/zO4bdceAhcIJIn20KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}