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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdaf1653f0d1306a1b3b8b08ec7b26d834063463e635683bc5fa78a67bf5cd90' 
  AND token = 'vIHRM7xTwVvAuTtVw7AqOb5UWU2duOchPI8ekQvhoVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}