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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b51812cc19ed74af5c69b0c66df784bd103a5f102c9172969aaedf28737a2ab2' 
  AND token = 'ICRbDj6DIZdRMj5J7aRT1HVkFAw/MzpAnMA4ih5xgiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}