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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ca05798fa5ba300b04e48e0cb640b109b3dc991dab6c9b8a06726636873712' 
  AND token = '2d2FOz17AeZUmS5bxPlvMGD8quhU86g7RUXt7ruVAW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}