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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5541c1066df5ab0b6f7e3933e13a41223d38e5b3a7d1727e63f13a0f7ccabab1' 
  AND token = 'naZL75qZ+dEGYSMNrQcwBcfuAgtsQsLov4uRFflu6gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}