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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457a379b9358ddb48dcb3ef32e8073b9bb39fea77050c639e53a4c2d2e5b003b' 
  AND token = '2SL91yR1VUKhSfk/I0FDoTz0BuuS8+pnzENpI//w+sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}