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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec0d7308b5a0ad3c6673e7b133c905bc9b45ea17bd7933298c0fa32204a2df12' 
  AND token = 'zoc21udx3nSssFHHnUe+GubkHMs6b6/okINs16Ho+r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}