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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7d97cfdd56292656e1c56ddd85a9f577da45e2dedda556a5e3e61552e3da656' 
  AND token = 'aYtQzin4TNIkgdoZ0AqwcCoa3EVgpeyIsWKDg2AYuZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}