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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45ec523b77a87bef012ec6ce95668ba867932cb1177da4536770ee8ab1607c5' 
  AND token = '9T9wg1TJ/Y/g6dZVAjRK555hX/5mbhcicKrhO/NcypI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}