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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4581a5d6338046c3089c01219bc80bdf84b928b18e4f92da03bb43a5c6cbe564' 
  AND token = 'zbx8vu/ovhYBmkr6bqcYBbUn1cbzK8JHj5/pc2KM2zQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}