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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e875ba1106f0052aab891f7dc9cfcad563a90ca6941647c9874d6fc8ff23e7e7' 
  AND token = 'zL6Avn6mqJxjY2c0Grt1hqRjktcFXIFu4ZsU11+Heh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}