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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f5a052a877da68d06443df2824f6b7a9ee8d78361f08bd9828bfea3ee97b60' 
  AND token = 'EqkroMEheLrnrIHn0Qau7TpJxL02ts3UReWc9ue+xJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}