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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66b9e59ead95fa8b7358944f3aee49f454f3f1427e03b6fa166eef0c03de48c' 
  AND token = 'pbfGjq65Sc46ip4NLcIA6aaLPu3Q+r5ci3bnCPNN6qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}