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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '774b0ac61fd587728968a7e43670cafde847c872000d48d62b96cfefee2c0de2' 
  AND token = '18HVZtwdmGO3ms4w/9EwHyVEzeiMjFerT5W+6IE4P/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}