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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6afeed3cbc18f92752dcbee51b56e2e60a52f197f06f4d4ee32fa63cb6a41496' 
  AND token = 'n3meAL5jbwra5p7RtXjTJ4eg//vTywzEId+35fTtl80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}