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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98cbb14a429a556faebca0de572030f7e2be85cfc3c4ec99d4e841a8f9670f46' 
  AND token = 'JdV3MT8MttCc3lrdu5Nzfx1UgHOnPFZFT24zicfTitQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}