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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfad8d342fb1720adafb19862d1d781c77270956f814b3bef08da5b70a70d8e1' 
  AND token = 'A0XHbBuuSJOyE05f/sVdb8Z4kn2ya6bs+/j/UY1YOsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}