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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2a7497183118314a77e139b8991b4e1d184ee9ab3a0b01606c4220e88a0052d' 
  AND token = 'poWtCoQ8fLaHjJNVcs6wHRZM823qfDdAjNpPRw12qQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}