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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89de836256262d8a865778779ffb7e4e68a5305f080bed809f14b2bf624ab1d6' 
  AND token = 'r1XpUaHN7MlPYFp/CeJYDZNfNaDTy+5R0RQ4yspPqdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}