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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dda7ed8e429670bee4b3d11bfdb2217e154aaec7ba297207b9c740994625426' 
  AND token = 'Bz+k7vDZPEJjzMkBckibwn4CWTEzkfU8/eOieJj9grA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}