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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd7d081265a1ee5fa8293d30c75a13798faea290b84b5acd2da1be5a41cf43e' 
  AND token = '2TMA4EA0NF0ll/wyxaOIh9Pjg8c+wk6lbdFyQNMv0kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}