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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2134551318dfca9d281ebbe0a2c8ef2399ea44c8e3d8c25f2254443a0294b74' 
  AND token = 'kvhjbZHZ+u9HpzrXj9XppIHRZk/4xNK4M2kEyf53FZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}