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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf09e54bea159216b994b5f3397231f812d4cef8dc4c01064ff6d19118d2f4f2' 
  AND token = 'C6lFEeAtDFu0G0WsABPNwDM/1H1nDvFpTLPVlI5tU/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}