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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a81fbf06173adb906f1806c9185227428b05e5cd041184a70dbd03dfb488925' 
  AND token = 'ILbStfkS/EBZt+bqN/by0mXN1ApfJQJoq8uAL3zvMaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}