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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c031c980d4303dd4897f5a64fb679ff0bcbc2ef31d4d7b65c8e9deed765b0f' 
  AND token = 'XBkOjSiSiY5V5ync6q02XSm1q4ReMfk32tCXSI7I+gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}